ChIRP探針

lncRNA ChIRP（Chromatin Isolation by RNA Purification）Probe是研究lncRNA分子作用機制的重要工具，它是一類生物素修飾的核酸探針。銳博生物提供業界領先的lncRNA分子序列設計及修飾探針合成服務，通過特異反義核酸序列組成的探針庫，與lncRNA高效雜交，再利用鏈霉親和素磁珠獲得目標lncRNA所結合的染色質復合體，最后純化的RNA、DNA和蛋白質可用于后續目標lncRNA分子作用機制的研究。

我要訂購

下載說明書

產品用途

1、lncRNA 結合蛋白鑒定
2、lncRNA 染色體結合位點鑒定
3、lncRNA 轉錄調控機制探索

產品優勢

1、設計優，多位點探針優化設計，全面提升雜交特異性
2、覆蓋全，lncRNA全鏈完整覆蓋，有效保證雜交效率

技術支持

Ribo? lncRNA ChIRP Probe實驗流程及應用

使用GAS5 lncRNA ChIRP Probe獲得與GAS5結合的RNA，ChIRP-RT-qPCR發現miR-196a結合在GAS5上。Wang K, et al. Biochemical and biophysical research communications, 2018.

代表性客戶文章

Ni C, Jiang W, Wang Z, et al. LncRNA-AC006129. 1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia[J]. Molecular psychiatry, 2020: 1-18.
Jin X, Xu X E, Jiang Y Z, et al. The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation[J]. Science advances, 2019, 5(3): eaat9820.
Lan T, Yuan K, Yan X, et al. LncRNA SNHG10 facilitates hepatocarcinogenesis and metastasis by modulating its homolog SCARNA13 via a positive feedback loop[J]. Cancer research, 2019, 79(13): 3220-3234.
Wang S, Zuo H, Jin J, et al. Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2[J]. Cell death & disease, 2019, 10(7): 1-15.

訂購產品

產品編號	產品名稱	目錄價
lnc4000982-1-2	h-AK096649_ChIRP-Probe(3bio)_4, 2nmol	¥580.00
lnc4000983-1-2	h-AK096649_ChIRP-Probe(3bio)_5, 2nmol	¥580.00
lnc4000984-1-2	h-AK096649_ChIRP-Probe(3bio)_6, 2nmol	¥580.00
lnc4000985-1-2	h-AK096649_ChIRP-Probe(3bio)_7, 2nmol	¥580.00
lnc4000986-1-2	h-AK096649_ChIRP-Probe(3bio)_8, 2nmol	¥580.00
lnc4000987-1-2	h-AK096649-AS_ChIRP-Probe(3bio)_1, 2nmol	¥580.00
lnc4000988-1-2	h-AK096649-AS_ChIRP-Probe(3bio)_2, 2nmol	¥580.00
lnc4001061-1-2	h-LINC00460(3bio)_1, 2nmol	¥580.00
lnc4001063-1-2	h-LINC00460(3bio)_3, 2nmol	¥580.00
lnc4001064-1-2	h-LINC00460(3bio)_4, 2nmol	¥580.00